論文などで使われているiPS細胞のクローンの情報を記載しています。
- 由来：PBMC (peripheral blood-derived mononuclear cells)、36Y、 Asian、 Male、 B
- 樹立方法：エピソーマルベクター（pCEセット、参考情報）
- 培地：StemFit AK03N (AJINOMOTO)
- 基質：iMatrix-511 (Matrixome)
- 臨床用iPS細胞ストックの製造法と同じ製法で作られたクローン
- 分化誘導実績のある細胞種：Primordial germ cells、Posterior Gut Progenitors、Ureteric bud organoids、Mesenchymal stem/stromal cells、Distinct Ocular Lineages、primordial germ-cell like cells (PGCLCs)
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, YamanakaS.
Scientific Reports 2014 Jan 8;4:3594. doi: 10.1038/srep03594
Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells.
Shihori Yokobayashi, Yukihiro Yabuta, Masato Nakagawa, Keisuke Okita, Bo Hu, Yusuke Murase, Tomonori Nakamura, Guillaume Bourque, Jacek Majewski, Takuya Yamamoto, Mitinori Saitou
Cell reports 37(5) 109909-109909 2021年11月2日
Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids.
Ran-Ran Zhang, Masaru Koido, Tomomi Tadokoro, Rie Ouchi, Tatsuya Matsuno, Yasuharu Ueno,Keisuke Sekine, Takanori Takebe,and Hideki Taniguchi
Stem Cell Reports. 2018 Mar 13; 10(3): 780–793. Published online 2018 Feb 8. doi: 10.1016/j.stemcr.2018.01.006
Site-specific randomization of the endogenous genome by a regulatable CRISPR-Cas9 piggyBac system in human cells.
Kentaro Ishida, Huaigeng Xu, Noriko Sasakawa, Mandy Siu Yu Lung, Julia Alexandra Kudryashev, Peter Gee, and Akitsu Hotta
Sci Rep. 2018; 8: 310. Published online 2018 Jan 10. doi: 10.1038/s41598-017-18568-4, PMID: 29321585
Protocol for the generation and expansion of human iPS cell-derived ureteric bud organoids.
Makoto Ryosaka, Shin-Ichi Mae, Kenji Osafune
STAR Protocols Volume 3, Issue 3, 16 September 2022, 101484
Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage.
Daisuke Kamiya, Nana Takenaka-Ninagawa, Souta Motoike, Mikihito Kajiya, Teppei Akaboshi, Chengzhu Zhao, Mitsuaki Shibata, Sho Senda, Yayoi Toyooka, Hidetoshi Sakurai, Hidemi Kurihara & Makoto Ikeya
npj Regenerative Medicine volume 7, Article number: 47 (2022)
Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages.
Shun Shibata, Ryuhei Hayashi, Toru Okubo, Yuji Kudo, Tomohiko Katayama, Yuki Ishikawa, Junko Toga, Emiko Yagi, Yoichi Honma, Andrew J. Quantock, Kiyotoshi Sekiguchi, Kohji Nishida
Cell Reports VOLUME 25, ISSUE 6, P1668-1679.E5, NOVEMBER 06, 2018, AccessDOI:https://doi.org/10.1016/j.celrep.2018.10.032
Effect of Rho–Associated Kinase Inhibitor on Growth Behaviors of Human Induced Pluripotent Stem Cells in Suspension Culture.
Takaki Matsumoto, Mee-Hae Kim and Masahiro Kino-oka
Bioengineering 2022, 9, 613. https://doi.org/10.3390/bioengineering9110613
Effect of liquid flow by pipetting during medium change on deformation of hiPSC aggregates.
Yuma Kato, Takuya Matsumoto, Masahiro Kino-oka
Regenerative Therapy 12 (2019) 20-26
Clonal variation of human induced pluripotent stem cells for induction into the germ cell fate.
Shihori Yokobayashi, Keisuke Okita, Masato Nakagawa, Tomonori Nakamura, Yukihiro Yabuta, Takuya Yamamoto, Mitinori Saitou
Biology of Reproduction, Volume 96, Issue 6, June 2017, Pages 1154–1166, https://doi.org/10.1093/biolre/iox038
A non-invasive method to generate induced pluripotent stem cells from primate urine.
Johanna Geuder, Lucas E. Wange, Aleksandar Janjic, Jessica Radmer, Philipp Janssen, Johannes W. Bagnoli, Stefan Müller, Artur Kaul, Mari Ohnuki & Wolfgang Enard
Scientific Reports volume 11, Article number: 3516 (2021)
Robust detection of undifferentiated iPSC among differentiated cells.
Keisuke Sekine, Syusaku Tsuzuki, Ryota Yasui, Tatsuya Kobayashi, Kazuki Ikeda, Yuki Hamada, Eriko Kanai, J. Gray camp, Barbara Treutlein, Yasuharu Ueno, Satoshi Okamoto & Hideki Taniguchi
Scientific Reports (2020) 10:10293 | https://doi.org/10.1038/s41598-020-66845-6
Oncogenic potential of human pluripotent stem cell-derived lung organoids with HER2 overexpression.
Akihiro Miura, Daisuke Yamada, Masahiro Nakamura, Shuta Tomida, Dai Shimizu, Yan Jiang, Tomoka Takao, Hiromasa Yamamoto, Ken Suzawa, Kazuhiko Shien, Masaomi Yamane, Masakiyo Sakaguchi, Shinichi Toyooka, Takeshi Takarada
MOLECULAR CANCER BIOLOGY 21 June 2021 https://doi.org/10.1002/ijc.33713
CRISPR-Cas3 induces broad and unidirectionalgenome editing in human cells.
Hiroyuki Morisaka, Kazuto Yoshimi, Yuya Okuzaki, Peter Gee, Yayoi Kunihiro,Ekasit Sonpho, Huaigeng Xu, Noriko Sasakawa, Yuki Naito, Shinichiro Nakada, Takashi Yamamoto,Shigetoshi Sano, Akitsu Hotta, Junji Takeda & Tomoji Mashimo
NATURE COMMUNICATIONS (2019)10:5302|https://doi.org/10.1038/s41467-019-13226-x
- 由来：PBMC (peripheral blood-derived mononuclear cells)、36Y、 Asian、 Male、 B
- 樹立方法：エピソーマルベクター（pCXLEセット、参考情報）
- 培地：StemFit AK03N (AJINOMOTO)
- 基質：iMatrix-511 (Matrixome)
- 分化誘導実績のある細胞種：Hematopoietic progenitor cells (HPCs)
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, YamanakaS.
Scientific Reports 2014 Jan 8;4:3594. doi: 10.1038/srep03594
Extracellular laminin regulates hematopoietic potential of pluripotent stem cells through integrin β1-ILK-β-catenin-JUN axis.
Akinori Yuzuriha, Sou Nakamura, Naoshi Sugimoto, Shunsuke Kihara, Masato Nakagawa, Takuya Yamamoto, Kiyotoshi Sekiguchi, Koji Eto
Stem cell research 53 102287-102287 2021年3月16日
- 由来：PBMC (peripheral blood-derived mononuclear cells)、38Y、 Asian、 Male、 A
- 樹立方法：エピソーマルベクター（pCEセット、参考情報）
- 培地：StemFit AK03N (AJINOMOTO)
- 基質：iMatrix-511 (Matrixome)
- 分化誘導実績のある細胞種：Cardiomyocytes
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, YamanakaS.
Scientific Reports 2014 Jan 8;4:3594. doi: 10.1038/srep03594
Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation.
Chikako Okubo, Megumi Narita, Azusa Inagaki, Misato Nishikawa, Akitsu Hotta, Shinya Yamanaka,and Yoshinori Yoshida
Stem Cell Reports j Vol. 16 j 1906–1922 j August 10, 2021
ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes.
Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C. Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto & Yoshinori Yoshida
Nature Communications volume 12, Article number: 3596 (2021)
- 由来：PBMC (peripheral blood-derived mononuclear cells)、24Y、 Female、O
- 樹立方法：エピソーマルベクター（pCEセット、参考情報）
- 培地：StemFit AK03N (AJINOMOTO)
- 基質：iMatrix-511 (Matrixome)
- 分化誘導実績のある細胞種：Cardiomyocytes
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, YamanakaS.
Scientific Reports 2014 Jan 8;4:3594. doi: 10.1038/srep03594
ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes.
Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C. Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto & Yoshinori Yoshida
Nature Communications volume 12, Article number: 3596 (2021)
- 由来：PBMC (peripheral blood-derived mononuclear cells)、50Y、 Male、JP
- 樹立方法：エピソーマルベクター（pCXLEセット、参考情報）
- 培地：StemFit 相当品
- 基質：iMatrix-511 相当品
- 分化誘導実績のある細胞種：Dopaminergic progenitors
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells.
Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, YamanakaS.
Scientific Reports 2014 Jan 8;4:3594. doi: 10.1038/srep03594
Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson’s Disease Model.
Hiromasa Adachi, Asuka Morizane, Sadaharu Torikoshi, Fabian Raudzus, Yukimasa Taniguchi, Susumu Miyamoto, Kiyotoshi Sekiguchi, Jun Takahashi
Stem Cells Translational Medicine, Volume 11, Issue 7, July 2022, Pages 767–777, https://doi.org/10.1093/stcltm/szac033
- iPS細胞研究財団から提供されています（詳細はこちら）。